PRP therapy and mesotherapy are both effective treatments for skin and tissue rejuvenation, but they differ in their approach and formulation. PRP therapy uses platelet-enriched plasma derived from the patient’s own blood, which is rich in growth factors and cytokines that promote tissue regeneration. This therapy can be applied to any skin layer, making it highly versatile. In contrast, mesotherapy involves the use of a nutrient-rich serum containing a blend of vitamins (such as A, B, C, E, and K), minerals like calcium and potassium, enzymes, hyaluronic acid, and amino acids. These ingredients are administered into the middle layer of the skin to hydrate, nourish, and improve overall skin tone. While PRP focuses on stimulating collagen production and repairing damaged tissues, mesotherapy is ideal for delivering hydration and essential nutrients to enhance the skin’s health and appearance.